OS1.8 IRE1-mediated immunomodulation in glioblastoma
نویسندگان
چکیده
منابع مشابه
Dual IRE1 RNase functions dictate glioblastoma development
Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Evidence suggests that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical role in cancer development. This concept is valid in glioblastoma multiform (GBM), the most lethal primary brain cancer with no effective treatment. We previously demonstrated...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2016
ISSN: 1523-5866,1522-8517
DOI: 10.1093/neuonc/now188.010